Almost 50% increase in Death Rate in the UK Middle-aged who never got Booster (#2*)
Comparison to the completely unvaccinated
*This post is an edit to the previous post of the same name.
When groups are compared in studies, and their age-specific death rates differ by 40% or more, it is a significant finding. Things that make you 40% more likely to die are very often clinically relevant and meaningful.
One thing that apparently has the power to make you 40% more likely to die, is getting fully-vaccinated but never going back for a booster dose — at least that is what UK data on those middle-aged appears to show.
Investigations will be required to discover why death rates were 40% higher among those who had taken two doses, but who had not had a booster shot for 6 months (they had had their final dose over 6 months ago).
The worst death increase from vaccination was in the age 60 to 64 group. The baseline monthly death rate for that group in the unvaccinated was 1033 monthly deaths per million.
But in the double-vaccinated group who never went back for a booster (2 doses over 6 months ago), the monthly death rate was 1508 monthly deaths per million — a 46% increase in the all-cause death rate.
Reference
“Table 6. Whole period counts of all cause deaths, deaths involving COVID-19 and deaths not involving COVID-19 … .” Age-standardised mortality rates for deaths by vaccination status, England: deaths occurring between 1 January 2021 and 31 March 2022: 16 May 2022. Age-standardised mortality rates for deaths involving COVID-19 by vaccination status, broken down by age group and sex. Deaths occurring between 1 January 2021 and 31 March 2022 in England. https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/datasets/deathsbyvaccinationstatusengland